{"id":14421,"date":"2018-01-06T16:57:05","date_gmt":"2018-01-06T20:57:05","guid":{"rendered":"https:\/\/vitamins.vitanetonline.com\/?p=14421"},"modified":"2018-08-17T15:43:57","modified_gmt":"2018-08-17T19:43:57","slug":"selenium-protects-a-specific-type-of-interneurons-in-the-brain","status":"publish","type":"post","link":"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/","title":{"rendered":"Selenium protects a specific type of interneurons in the brain"},"content":{"rendered":"<div class=\"richsummary\">\n<p id=\"abstract\">Furthermore, the scientists were able to show that ferroptosis is triggered by oxidative stress, which is known to occur for instance during high metabolic activity of cells and high neuronal activity. In future investigations, study leader Marcus Conrad and his team aim to investigate how ferroptosis is triggered in cells. In further studies, we were able to show that these neurons were lost during postnatal development, when sulfur- instead of selenium-containing GPX4 was present,&#8221; stated first author of the study, Irina Ingold. In order to better understand the role of GPX4 in this death process, we established and studied mouse<\/p>\n<p id=\"takeawayheader\">Key Takeaways:<\/p>\n<ul id=\"takeaways\">\n<li id=\"takeaway1\">A German research center studies the effects of lifestyle, environment, and genetics on human diseases.<\/li>\n<li id=\"takeaway2\">The researchers discovered that cells containing the selenium normally make up a subgroup within all brain cells and that this subgroup was killed off during infancy when selenium was not available to<\/li>\n<li id=\"takeaway3\">In a study on mouse brain cells, the cells which did not have selenium available instead used sulfur which resulted in the death of the mice within 3 weeks.<\/li>\n<\/ul>\n<p id=\"quote\">&#8220;Selenium-containing GPX4 protects these specialized neurons from oxidative stress and from ferroptotic cell death.&#8221;<\/p>\n<p><span id=\"readmoretext\">Read more: <\/span>https:\/\/www.eurekalert.org\/pub_releases\/2017-12\/hzm&#8211;spa122917.php<\/p>\n<\/div>\n<div id=\"task_trail\" style=\"display:none\">(abstract 37NXA7GVST7W2T87K3S66YKPNTIVL8 3P59JYT76LLEBZG3W4FOE4TIBUAT2E AS7D4MNIH56ND)(authorquote 39KV3A5D188HVG21MEMRC6IHT5KS7S 3I0BTBYZAXM3WBCJRNY93XSITYBY0R A34MRQ1OP87XC6)(keypoints 3KWGG5KP6J3K92KSTYYGGJBP2R2MCC 3XXU1SWE8MW20TEGBHKT0BABR86A0U AKP3UXJ0TDPVO)<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Furthermore, the scientists were able to show that ferroptosis is triggered by oxidative stress, which is known to occur for instance during high metabolic activity of cells and high neuronal activity. In future investigations, study leader Marcus Conrad and his team aim to investigate how ferroptosis is triggered in cells. In further studies, we were [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":6054,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[1646],"tags":[],"class_list":{"0":"post-14421","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-commentary-posts","8":"entry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.3 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Selenium protects a specific type of interneurons in the brain - Vitamins and Their Uses<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Selenium protects a specific type of interneurons in the brain\" \/>\n<meta property=\"og:description\" content=\"Furthermore, the scientists were able to show that ferroptosis is triggered by oxidative stress, which is known to occur for instance during high metabolic activity of cells and high neuronal activity. In future investigations, study leader Marcus Conrad and his team aim to investigate how ferroptosis is triggered in cells. In further studies, we were [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\" \/>\n<meta property=\"og:site_name\" content=\"Vitamins and Their Uses\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/VitaNetVitaminStore\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-01-06T20:57:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-08-17T19:43:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/vitanet-img-322.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"740\" \/>\n\t<meta property=\"og:image:height\" content=\"387\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Darrell Miller\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@VitaNetLLC\" \/>\n<meta name=\"twitter:site\" content=\"@VitaNetLLC\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Darrell Miller\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\"},\"author\":{\"name\":\"Darrell Miller\",\"@id\":\"https:\/\/vitamins.vitanetonline.com\/#\/schema\/person\/a3eedc2c7990409bef85f084dfb1f853\"},\"headline\":\"Selenium protects a specific type of interneurons in the brain\",\"datePublished\":\"2018-01-06T20:57:05+00:00\",\"dateModified\":\"2018-08-17T19:43:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\"},\"wordCount\":267,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/vitamins.vitanetonline.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/vitanet-img-322.jpg\",\"articleSection\":[\"Commentary\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\",\"url\":\"https:\/\/vitamins.vitanetonline.com\/index.php\/selenium-protects-a-specific-type-of-interneurons-in-the-brain\/\",\"name\":\"Selenium protects a specific type of interneurons in the brain - 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