{"id":6707,"date":"2016-06-23T19:24:06","date_gmt":"2016-06-23T23:24:06","guid":{"rendered":"http:\/\/vitamins.vitanetonline.com\/?p=6707"},"modified":"2016-06-19T20:57:50","modified_gmt":"2016-06-20T00:57:50","slug":"health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce","status":"publish","type":"post","link":"https:\/\/vitamins.vitanetonline.com\/index.php\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\/","title":{"rendered":"Health risk of High Levels of Homocysteine and how Vitamin B12 can be used to reduce it"},"content":{"rendered":"<p>Homocysteine is a common amino acid found in the blood and it is acquired through consumption of meat. High levels of homocysteine are associated to the early development of heart and blood vessel disease. High level is considered to be an independent risk factor for the heart disease.<\/p>\n<p>&nbsp;<\/p>\n<p>High homocysteine is associated with low levels of vitamin B12, B6, foliate and renal disease. In fact individuals suffering from cardiovascular disease, migraines, stroke and dementia could be suffering from the effects of elevated levels of homocysteine. Replacing these vitamins often helps to bring the level of homocysteine to normal.<\/p>\n<p>Genetic disorders may also affect the ability of the body to metabolize homocysteine into cysteine, this may result to elevated levels of homocysteine in the urine and blood. Screening is highly recommended especially in infants if there is family history of this disease.\u00a0Other possible causes include: low levels of kidney disease, thyroid hormone, psoriasis, some medicines or if the condition spreads into your family.<\/p>\n<p>&nbsp;<\/p>\n<h3>Potential Risks associated with High Levels of Homocysteine<\/h3>\n<ul>\n<li>Higher levels of elevated homocysteine would affect the inner lining of blood vessels with an individual\u2019s body, this results to increase of risk of atherosclerosis or narrowing of blood vessels. This can lead to heart attack and stroke. The risk of pulmonary thrombosis and deep vein thrombosis can also be associated with high levels of homocysteine in the body.<\/li>\n<li>Infants born with the genetic condition of <em>homocystinuria<\/em>, the inherited disorders affect the body\u2019s metabolism of homocysteine to cysteine. This leads to the dislocation of lens in the eye, marfan type appearance, sunken chest, seizures and mental retardation. Neonatal strokes may also crop up with high level of homocysteine.<\/li>\n<li>There is a correlation between homocysteine levels in the body and the size of the carotid arteries which supply the brain with blood, hence the higher the homocysteine levels the more stenosed the carotid artery.\u00a0It also causes Alzheimers disease and some other types of dementia which are occasionally diagnosed with most patients.<\/li>\n<li>In pregnancy period, homocysteine levels tend to go down. High levels may be associated with fetal abnormalities that go long potential blood vessel problems in the placenta which may result to abruption.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>How Vitamin B12 helps lower high levels of Homocysteine<\/h3>\n<p>The key to containing the runaway of homocysteine is by changing the amino acid back into harmless amino acid methionine through a normal process known as <em>remethylation<\/em>. In order to accomplish remethylation, the body needs sufficient amount of vitamin B12. In the absence of this cofactor, there will be a resultant accumulation of homocysteine to toxic levels which can be destructive to cognitive function in the brain.<\/p>\n<p>The treatment for homocysteine can be done through vitamin supplementation. The vitamin can be found in wide variety of fruits, leafy vegetables, asparagus, lentils and fortified grain products that are fortified with folic acid.<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\" wp-image-6708 aligncenter\" src=\"http:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/VitaminB12Foods-300x225.jpg\" alt=\"VitaminB12Foods\" width=\"368\" height=\"276\" \/><\/p>\n<p>Vegetarians who do not supply their diet with vitamin B12 may have low levels of homocysteine and vitamin B12. These conditions are especially associated with brain atrophy and dementia, though there is an evidence for birth defects, low bone mineral density and stroke.<\/p>\n<p>Some patients don\u2019t respond to vitamin supplementation. They are therefore considered to be pyridoxine-resistant. A diet low in methionine would be the most appropriate in addition to the vitamin B12.<\/p>\n<p>&nbsp;<\/p>\n<p><!--more--><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/vitanetonline.com\/description\/4344\/vitamins\/Vitamin-B12-Gumlet\/\"><img decoding=\"async\" class=\"alignnone size-medium wp-image-6703\" src=\"http:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/076280043440-2-300x300.jpg\" alt=\"076280043440\" width=\"300\" height=\"300\" srcset=\"https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/076280043440-2-300x300.jpg 300w, https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/076280043440-2-150x150.jpg 150w, https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/076280043440-2.jpg 500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Homocysteine is a common amino acid found in the blood and it is acquired through consumption of meat. High levels of homocysteine are associated to the early development of heart and blood vessel disease. High level is considered to be an independent risk factor for the heart disease. &nbsp; High homocysteine is associated with low [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[392],"tags":[1795,1806],"class_list":{"0":"post-6707","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-amino-acids","7":"tag-homocysteine","8":"tag-risks","9":"entry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Health risk of High Levels of Homocysteine and how Vitamin B12 can be used to reduce it - Vitamins and Their Uses<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vitamins.vitanetonline.com\/index.php\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Health risk of High Levels of Homocysteine and how Vitamin B12 can be used to reduce it\" \/>\n<meta property=\"og:description\" content=\"Homocysteine is a common amino acid found in the blood and it is acquired through consumption of meat. High levels of homocysteine are associated to the early development of heart and blood vessel disease. High level is considered to be an independent risk factor for the heart disease. &nbsp; High homocysteine is associated with low [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/vitamins.vitanetonline.com\/index.php\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\/\" \/>\n<meta property=\"og:site_name\" content=\"Vitamins and Their Uses\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/VitaNetVitaminStore\/\" \/>\n<meta property=\"article:published_time\" content=\"2016-06-23T23:24:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/vitamins.vitanetonline.com\/wp-content\/uploads\/VitaminB12Foods.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"768\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Corey B\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@VitaNetLLC\" \/>\n<meta name=\"twitter:site\" content=\"@VitaNetLLC\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Corey B\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/\"},\"author\":{\"name\":\"Corey B\",\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/#\\\/schema\\\/person\\\/2b2ac12daebe2519c5b9f4abfc54d1c3\"},\"headline\":\"Health risk of High Levels of Homocysteine and how Vitamin B12 can be used to reduce it\",\"datePublished\":\"2016-06-23T23:24:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/\"},\"wordCount\":573,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/vitamins.vitanetonline.com\\\/wp-content\\\/uploads\\\/VitaminB12Foods-300x225.jpg\",\"keywords\":[\"Homocysteine\",\"Risks\"],\"articleSection\":[\"Amino Acids\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/\",\"url\":\"https:\\\/\\\/vitamins.vitanetonline.com\\\/index.php\\\/health-risk-high-levels-homocysteine-vitamin-b12-can-used-reduce\\\/\",\"name\":\"Health risk of High Levels of Homocysteine and how Vitamin B12 can be used to reduce it - 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