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The Connection between Gut Dysbiosis, Type 2 Diabetes, and SCFAs

Is Type 2 Diabetes Actually a Gut Problem? The Link Between Dysbiosis and Blood Sugar and SCFAs

December 17, 2025 By Darrell Miller Leave a Comment

Yes, substantial evidence suggests that Type II Diabetes (T2D) is strongly linked to gut dysbiosis and a subsequent deficiency in Short-Chain Fatty Acids (SCFAs). Research increasingly views the gut microbiome not just as a bystander in diabetes, but as a driving factor. In many cases, low production of SCFAs (specifically butyrate, propionate, and acetate) acts as a "metabolic brake" that … [Read More...]

FEATURES

The Gut Kidney Axis

Can SCFAs Help Improve Kidney Function and Microcirculation, are the Two Connected and What About Glycocalyx?

December 16, 2025 By Darrell Miller Leave a Comment

Yes, lets take a look, Short-Chain Fatty Acids (SCFAs) can help improve both kidney function and microcirculation, and the two are deeply connected. In fact, the health of your kidneys is almost entirely dependent on microcirculation (blood flow in the smallest vessels), and SCFAs are emerging as a critical “signaling bridge” that protects these tiny […]

The Gut Heart Axis, Leaking Valve and SCFAs

Heart Trouble, The Gut-Heart Axis, Edema and SCFAs

December 15, 2025 By Darrell Miller Leave a Comment

When a person has a leaky heart valve, it causes other health issues like edema. What happens to the heart that causes the valve to start leaking in the first place? Is there cartilage involved or the breakdown of cartilage? Is there a way to naturally repair the valve? Can SCFAs help in the repair […]

Coffee Consumption and SCFA production in the body

Can Coffee Affect Gut Diversity And Reduce SCFAs?

December 14, 2025 By Darrell Miller Leave a Comment

Research indicates that for most people, moderate coffee consumption increases gut microbiome diversity and promotes the production of short-chain fatty acids (SCFAs), rather than reducing them. However, the premise about “reducing” SCFAs might stem from confusion with the effects of excessive caffeine intake or specific digestive conditions (like IBS) where coffee can trigger motility issues […]

Soda Pop can contribute to a reduction in SCFAs production which will impact your health!

Can Soda Pop Products Cause Gut Dysbiosis And Lower SCFA Production?

December 13, 2025 By Darrell Miller Leave a Comment

Yes, current research indicates that soda pop products – both regular (sugar-sweetened) and diet (artificially sweetened) – can contribute to gut dysbiosis and significantly lower the production of Short-Chain Fatty Acids (SCFAs). The mechanisms differ slightly depending on whether the soda contains high-fructose corn syrup (HFCS) or artificial sweeteners, but the end result is often […]

Alcohol causes Gut Dysbiosis and reduces SCFAs

Does Alcohol Cause Gut Disbiosis And Reduce SCFA Production?

December 13, 2025 By Darrell Miller Leave a Comment

Yes, alcohol consumption is a well-established cause of gut dysbiosis and directly leads to a reduction in Short-Chain Fatty Acid (SCFA) production, particularly butyrate. Research indicates that ethanol acts as a solvent and a toxin that disrupts the intestinal ecosystem, favoring pro-inflammatory pathogens over the commensal bacteria responsible for fermentation. 1. Mechanism of Alcohol-Induced Dysbiosis […]

All Sugar Causes Gut Dysbiosis!

Can Sugar Cause Gut Dysbiosis and Slow SCFAs Production by Friendly Bacteria

December 13, 2025 By Darrell Miller Leave a Comment

Yes, high sugar intake can cause gut dysbiosis and significantly reduce the production of Short-Chain Fatty Acids (SCFAs).1 In a healthy gut, beneficial bacteria ferment dietary fiber to produce SCFAs (like butyrate), which fuel your gut cells and lower inflammation.2 When you consume excess sugar, you disrupt this ecosystem, effectively “starving” the good bacteria and […]

SCFAs and an acidic colon environment and its effects on Pesticides and PFAs

Can The Acidic Environment That SCFAs Produce in The Colon Slow Down The Absorption of Pesticides And PFAs?

December 12, 2025 By Darrell Miller Leave a Comment

This is a complex biological question where the answer depends on whether you look at the chemistry of the toxins or the biology of the gut wall. The short answer is: Physically, yes, but chemically, it might actually do the opposite. While SCFAs (Short-Chain Fatty Acids) are incredibly protective, the acidity they produce (lowering the […]

Understanding Grey Hair Causes And The SCFAs Connection

December 12, 2025 By Darrell Miller Leave a Comment

Aging hair is rarely caused by a single deficiency. While mineral shortages can play a role, the primary cause is now understood to be a specific type of stem cell failure. Here is a breakdown of the biological mechanisms behind grey hair, addressing the questions about minerals and Short-Chain Fatty Acids (SCFAs). 1. Is it […]

SCFAs might help free testosterone levels

Can SCFAs Slow Down The Conversion of Free Circulating Testosterone to Estrogen

December 12, 2025 By Darrell Miller Leave a Comment

Yes, there is evidence that Short-Chain Fatty Acids (SCFAs) – specifically butyrate – can slow down the conversion of testosterone to estrogen. They do this through two distinct pathways: a direct mechanism where butyrate suppresses the “conversion enzyme” itself, and an indirect mechanism where SCFAs reduce the body fat that drives this conversion. Here is […]

The Connection between the Gut-Brain Axis and Depression

Can SCFAs Help With People Who Suffer From Depression? Is Depression A Symptom Of Gut Dysbiosis?

December 11, 2025 By Darrell Miller Leave a Comment

Recent research into the “gut-brain axis” offers a promising perspective on this question. In short, Yes, Short-Chain Fatty Acids (SCFAs) can help with depression, and there is substantial evidence linking depression to gut dysbiosis. The relationship is less like a simple “symptom” and more like a bidirectional cycle – gut health affects mood, and mood […]

COMMENTARY

Alcohol damaged the gut barrier and more

An Interesting Fact: The “double jeopardy” Relationship Between Alcohol And Your Gut.

December 16, 2025 By Darrell Miller Leave a Comment

The Fact: Alcohol Sabotages the Gut's "Repair Crew" The most fascinating - and damaging - … [Read More...]

The Microbiome Kidney connection

An interesting fact that bridges the gap between your gut microbiome and renal function.

December 16, 2025 By Darrell Miller Leave a Comment

The Kidneys Can "Smell" Short-Chain Fatty Acids It sounds like science fiction, but your … [Read More...]

SCFAs can switch genes on!

Interesting Fact: SCFAs act as an “Epigenetic Switches”

December 12, 2025 By Darrell Miller Leave a Comment

Yes, "SCFAs act as an "Epigenetic Switches" You might already know SCFAs (like butyrate) … [Read More...]

pure water

Toxic Water Contaminants Implicated in Parkinson’s Disease

June 11, 2024 By Darrell Miller Leave a Comment

The article on Dr. Mercola's website discusses a significant link between … [Read More...]

magnesium

How Important is Magnesium for Optimal Health?

December 24, 2022 By Darrell Miller Leave a Comment

You may not think much about magnesium, but it is a very important mineral needed for … [Read More...]

taylor coffee

Understanding the Benefits of Organic Acid-Free Coffee

December 22, 2022 By Darrell Miller Leave a Comment

If you’re a coffee lover, then you know that there’s nothing quite like a cup of freshly … [Read More...]

The Surprising Benefits of Cranberry Powder for Adult Cardiovascular Health

December 17, 2022 By Darrell Miller Leave a Comment

For many men and women, taking care of your cardiovascular health is a priority. But did … [Read More...]

exercise

The Benefits of L-Citrulline for Athletic Performance

December 9, 2022 By Darrell Miller Leave a Comment

When it comes to boosting athletic performance, many athletes turn towards supplements to … [Read More...]

Glutamine white powder

What You Need to Know About L-Glutamine and Gut Health

December 3, 2022 By Darrell Miller Leave a Comment

If you’ve been researching digestive health, chances are you’ve come across L-Glutamine. … [Read More...]

d-mannose powder

D-Mannose and Bladder Infections

November 11, 2022 By Darrell Miller Leave a Comment

A bladder infection occurs when bacteria enters the urinary tract and multiplies in the … [Read More...]

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