Can SFCAs from good gut health improve sleep? Yes, research into the gut-brain axis suggests a powerful connection between short-chain fatty acids (SCFAs) and sleep quality. While the science is still evolving, current evidence (including studies from 2024 and 2025) indicates that a healthy gut … [Read more...]
Archives for December 2025
Interesting Facts about SCFAs that research has discovered in 2025 and 2026
Let’s dive into some of the most cutting-edge and obscure research from 2024 and 2025. 1. The "Butyrate Paradox" in the Colonic Crypt While we know butyrate is the primary fuel for colonocytes, its distribution is actually a spatial signal for stem cell protection. The Gradient: Butyrate … [Read more...]
Precision vs. Broad-Spectrum: How Cloves, Wormwood, and Black Walnut Break the Parasite Life Cycle Vs Ivermectin.
Comparing the herbal trio of Black Walnut, Wormwood, and Clove to the pharmaceutical Ivermectin is a classic "Natural vs. Synthetic" debate. While both are used to combat parasites, they operate on different scales of potency, safety, and scientific validation. Which Kills More Parasites? The … [Read more...]
Can The Lack of Soluble Fiber Cause Alzheimer’s Over a Lifetime Due to Poor SCFA Production?
Recent research suggests a strong link between a lifetime of low soluble fiber intake and an increased risk of developing Alzheimer’s disease and other forms of dementia. While "cause" is a complex term in medical science, a lack of soluble fiber is now considered a significant, modifiable risk … [Read more...]
The Alkaline Myth: Why Baking Soda Might Be Starving Your Good Gut Bacteria
"Can taking baking soda cause a pH rise in the digestive tract and reduce SCFA production?" The answer is yes, it is theoretically possible, but it depends heavily on frequency and dosage. If pH (becoming more alkaline) in the wrong part of the gut, it can indeed inhibit Short-Chain Fatty Acid … [Read more...]
Is Your Gut Fueling Your Autoimmunity? The Missing Link in Type 1 Diabetes Management
Yes, current research strongly supports the link between Type 1 Diabetes (T1D), gut dysbiosis, and low Short-Chain Fatty Acids (SCFAs). While T1D is an autoimmune condition, the "gut factor" is increasingly viewed as a critical environmental trigger that may turn on the genetic … [Read more...]
Is Type 2 Diabetes Actually a Gut Problem? The Link Between Dysbiosis and Blood Sugar and SCFAs
Yes, substantial evidence suggests that Type II Diabetes (T2D) is strongly linked to gut dysbiosis and a subsequent deficiency in Short-Chain Fatty Acids (SCFAs). Research increasingly views the gut microbiome not just as a bystander in diabetes, but as a driving factor. In many cases, low … [Read more...]
An Interesting Fact: The “double jeopardy” Relationship Between Alcohol And Your Gut.
The Fact: Alcohol Sabotages the Gut's "Repair Crew" The most fascinating - and damaging - aspect of alcohol consumption isn't just that it directly damages the gut wall; it is that it systematically starves the cells attempting to repair that damage. This creates a vicious cycle known as … [Read more...]
An interesting fact that bridges the gap between your gut microbiome and renal function.
The Kidneys Can "Smell" Short-Chain Fatty Acids It sounds like science fiction, but your kidneys possess olfactory receptors - the same type of sensors found in your nose - specifically tuned to detect Short-Chain Fatty Acids (SCFAs) circulating in your blood. Here is the breakdown of this … [Read more...]
Can SCFAs Help Improve Kidney Function and Microcirculation, are the Two Connected and What About Glycocalyx?
Yes, lets take a look, Short-Chain Fatty Acids (SCFAs) can help improve both kidney function and microcirculation, and the two are deeply connected. In fact, the health of your kidneys is almost entirely dependent on microcirculation (blood flow in the smallest vessels), and SCFAs are emerging as … [Read more...]
Heart Trouble, The Gut-Heart Axis, Edema and SCFAs
When a person has a leaky heart valve, it causes other health issues like edema. What happens to the heart that causes the valve to start leaking in the first place? Is there cartilage involved or the breakdown of cartilage? Is there a way to naturally repair the valve? Can SCFAs help in the repair … [Read more...]
Can Coffee Affect Gut Diversity And Reduce SCFAs?
Research indicates that for most people, moderate coffee consumption increases gut microbiome diversity and promotes the production of short-chain fatty acids (SCFAs), rather than reducing them. However, the premise about "reducing" SCFAs might stem from confusion with the effects of excessive … [Read more...]
Can Soda Pop Products Cause Gut Dysbiosis And Lower SCFA Production?
Yes, current research indicates that soda pop products - both regular (sugar-sweetened) and diet (artificially sweetened) - can contribute to gut dysbiosis and significantly lower the production of Short-Chain Fatty Acids (SCFAs). The mechanisms differ slightly depending on whether the soda … [Read more...]
Does Alcohol Cause Gut Disbiosis And Reduce SCFA Production?
Yes, alcohol consumption is a well-established cause of gut dysbiosis and directly leads to a reduction in Short-Chain Fatty Acid (SCFA) production, particularly butyrate. Research indicates that ethanol acts as a solvent and a toxin that disrupts the intestinal ecosystem, favoring … [Read more...]
Can Sugar Cause Gut Dysbiosis and Slow SCFAs Production by Friendly Bacteria
Yes, high sugar intake can cause gut dysbiosis and significantly reduce the production of Short-Chain Fatty Acids (SCFAs).1 In a healthy gut, beneficial bacteria ferment dietary fiber to produce SCFAs (like butyrate), which fuel your gut cells and lower inflammation.2 When you consume excess … [Read more...]
Can The Acidic Environment That SCFAs Produce in The Colon Slow Down The Absorption of Pesticides And PFAs?
This is a complex biological question where the answer depends on whether you look at the chemistry of the toxins or the biology of the gut wall. The short answer is: Physically, yes, but chemically, it might actually do the opposite. While SCFAs (Short-Chain Fatty Acids) are incredibly … [Read more...]
Interesting Fact: SCFAs act as an “Epigenetic Switches”
Yes, "SCFAs act as an "Epigenetic Switches" You might already know SCFAs (like butyrate) are fuel for your gut cells. But the surprising part is that they don't just fuel cells - they enter the nucleus of your cells and physically alter the shape of your DNA packaging to toggle genes on and … [Read more...]
Understanding Grey Hair Causes And The SCFAs Connection
Aging hair is rarely caused by a single deficiency. While mineral shortages can play a role, the primary cause is now understood to be a specific type of stem cell failure. Here is a breakdown of the biological mechanisms behind grey hair, addressing the questions about minerals and Short-Chain … [Read more...]
Can SCFAs Slow Down The Conversion of Free Circulating Testosterone to Estrogen
Yes, there is evidence that Short-Chain Fatty Acids (SCFAs) - specifically butyrate - can slow down the conversion of testosterone to estrogen. They do this through two distinct pathways: a direct mechanism where butyrate suppresses the "conversion enzyme" itself, and an indirect mechanism where … [Read more...]
Can SCFAs Help With People Who Suffer From Depression? Is Depression A Symptom Of Gut Dysbiosis?
Recent research into the "gut-brain axis" offers a promising perspective on this question. In short, Yes, Short-Chain Fatty Acids (SCFAs) can help with depression, and there is substantial evidence linking depression to gut dysbiosis. The relationship is less like a simple "symptom" and more like … [Read more...]
Does SCFAs Thyroid Function and Help Slow Down Hashimoto Disease?
The short answer is yes. Short-Chain Fatty Acids (SCFAs) - particularly butyrate - appear to play a significant protective role in thyroid function and may help slow the progression of Hashimoto’s thyroiditis. Because Hashimoto’s is primarily an autoimmune condition (where the immune system … [Read more...]
Can SCFAs Strengthen Bone Marrow and Red Blood Cells Production and Formation?
Research indicates that Short-Chain Fatty Acids (SCFAs) - particularly butyrate and propionate - play a significant, supportive role in bone marrow function and red blood cell formation. While most evidence comes from pre-clinical studies (animal and cell models), the "Gut-Bone Marrow Axis" is a … [Read more...]
Can SCFAs Help Bone Formation? Can it Assist in Preventing Bone Loss?
Yes, current research indicates that Short-Chain Fatty Acids (SCFAs) can act as a "double-agent" for bone health: they both stimulate new bone formation and prevent bone loss. This connection is now widely referred to by scientists as the "Gut-Bone Axis," a communication highway where the health … [Read more...]
SCFAs Benefit the Lungs Via Gut-Lung Axis
The short answer is Yes, Short-Chain Fatty Acids (SCFAs)—specifically butyrate, propionate, and acetate - have a profound and generally positive effect on the lungs and lung function. This connection is known as the "Gut-Lung Axis." It describes how the health of your gut microbiome directly … [Read more...]
Can SCFAs Help Build A Healthy Stomach Lining?
Yes, Short-Chain Fatty Acids (SCFAs)—particularly butyrate—can help build, protect, and repair the stomach lining. While SCFAs are most famous for their role in the colon (large intestine), recent research shows they also play a critical role in gastric (stomach) health. They act as a "shield" … [Read more...]