This is an interesting idea, that the inflammatory process of individuals type 1 diabetes is different than others with various other autoimmune diseases. It’s an interesting article but it doesn’t really delineate if the changes an inflammation, the unique signature, is a precursor or the result of the disease process or genetic specific findings in patients with type 1 diabetes. In other words which came first? I would like to see an article about that or any findings. Also I am curious about the microbiome itself and how it is different from others with autoimmune disease and further information the actual gut Flora.
Key Takeaways:
- The investigators examined the microbiome of the 54 patients, which allowed them to directly assess the gastrointestinal tract and bacteria, unlike other studies that relied on stool samples or analysis.
- The analysis of tissues sampled from the endoscopy produced high-resolution snapshots of the innermost layer of the gastrointestinal tract, according to the study.
- Additionally, the participants with type 1 diabetes showed a distinct combination of gut bacteria that differed from the other 2 groups.
“The results of the study showed individuals with type 1 diabetes had significantly more signs of inflammation of the gut’s mucous membrane linked to 10 specific genes compared with healthy controls and individuals with celiac disease.”
https://www.google.com/url?rct=j&sa=t&url=http://www.specialtypharmacytimes.com/news/gut-bacteria-plays-a-role-in-type-1-diabetes&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNFnSy-yEq4Tfxg4CTWTgwx4Gr8xsQ