Chronic inflammation observed in diabetes patients is one of the leading causes of these complications. The researchers found that when specific immune cells, called macrophages, are unable to manufacture their fat, the chance of chronic inflammation and reducing diabetes, even if mice eat a high-fat diet. Synthesis of fats inside macrophages is mediated by an enzyme fatty acid synthase. When it is active, FAS promotes specific changes on the membranes of macrophages, which makes them responsive to fat consumed from the diet and activates chronic inflammation.
Key Takeaways:
- Diabetes is a chronic condition that often leads to multiple complications, such as decreased kidney function, heart attacks and strokes.
- The number of diabetes patients keeps increasing, and despite major advances made in the last few decades for the control of blood sugar, patients still suffer from numerous diabetes complications.
- This suggests that high blood sugar is not the whole story. Inflammation that accompanies diabetes seems to be doing a lot of damage, independently of sugar.
“Diabetes is a chronic condition that often leads to multiple complications, such as decreased kidney function, heart attacks and strokes.”
https://www.google.com/url?rct=j&sa=t&url=http://www.medicalnewsbulletin.com/cause-chronic-inflammation-diabetes/&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNHAn-xWY43YZhjdV6vd5Yj8CjQvVw