Magnesium is very crucial in the body. It is one of the most abundant minerals in the body and plays a major role in various physiologic processes. It is also known to increase neuromuscular transmission and activity. Magnesium deficiency increases neuromuscular excitability. If there is a deficit in magnesium, there is release of acetylcholine from the presynaptic membrane that is located in the nerve fibers.
If magnesium is excess in the body, it is known to cause a sedative effect. This effect takes place in the neuromuscular system where it results in the loss of reflexes in deep tendons. Magnesium therefore plays a major role in influencing neuromuscular activity in our body.
Why Magnesium is Important to Neuromuscular Transmission?
It is also worth noting that this mineral transmits neuromuscular activity in our bodies by acting as a major mediator of all neural transmission processes that occur in the central nervous system. You can use the concentration of magnesium in the serum to clearly understand or assess the status of magnesium in our bodies. The muscle contains approximately 30 percent of the total concentration of magnesium in our body. This therefore means that you can use the tissue to clearly understand the status of magnesium in your body.
This mineral is actually very crucial in our bodies because it is very important in neurotransmission where it responsible for orchestrating memory, mood, cognition, relaxation and also sleep. Magnesium also interacts with certain receptors and neurotransmitters that are mostly synthesized from a single neuron. The neuron then releases it to the synapse, which is the space located between two neurons and are mostly recognized by a neuron via a particular receptor.
The mineral is very important in the synthesis of neurotransmitters like serotonin, that maintain cognitive functions, healthy mood, responses to stress, appetite and also behaviour. Finally, magnesium is known to interact with receptors located in the postsynaptic neuron. It therefore works to increase neuromuscular transmission and activity.