Neurotransmitters

What is Phosphatidylcholine And How Does It Boost Cellular Health, Cognitive Function And More?

Phosphatidylcholine For Better Health

Phosphatidylcholine is an organic compound that naturally occurs in nature. It was the first constituent of lecithin to be isolated from egg yolk, and as such often used interchangeably with lecithin. It has become one of the most popular dietary supplements that contain precursors of choline, which is an essential nutrient. Phosphatidylcholine is a phospholipid found in cell membranes of all cells.

The scientific community is convinced that high levels of phosphatidylcholine are necessary for a healthy body, drawing on the fact that the phosphatidylcholine dwindle in number as we age. It is postulated that depleting levels of phosphatidylcholine contribute to the process of aging. Regular intake of foods high in phosphatidylcholine has been linked to the alleviation of many diseases, such as chronic hepatitis and Alzheimer’s disease. Supplementation certainly impacts the health of cells.

Phosphatidylcholine And Your Body

Promotes Cellular Health

Phosphatidylcholine is an important component of cells. As a phospholipid, it is present in every cell, making up the lipid bilayer of cell membranes. Its presence in the lipid bilayer supports both intracellular and intercellular activities of each individual cell. It enables the lipid bilayer to properly keep ions and molecules where they should be and allow them to move at the right time, which is central to maintaining the pH level of the body. It also appears to modulate the effects of cell-to-cell communication.

Enhances Cognitive Function

Supplementation of phosphatidylcholine is certain to benefit the mental health of both the young and the elderly. It affects neuronal activities, promoting an influx of chemical compounds that help maintain brain function and creating homeostasis in the nervous system. It is often marketed to young people largely owing to its nootropic properties, but it is also important for people of old age. It has been reported numerous times that high levels of phosphatidylcholine prevent brain shrinking and delay the onset of degenerative mental disorders, most notably Alzheimer’s disease.

Prevents Cardiovascular Diseases

There have been numerous citations on the anti-inflammatory effects of phosphatidylcholine, especially in the prevention of cardiovascular diseases. For one, it is a biological precursor of choline, which is important in maintaining cardiovascular health. Low levels of choline cause an increase in the serum levels of the amino acid homocysteine. High concentrations of homocysteine contributes to inflammation tied to atherosclerosis and related disorders. Recent studies reveal that homocysteine levels can’t be reversed, but can be prevented with supplementation of phosphatidylcholine.

Displays Hepatoprotective Properties

Phosphatidylcholine is especially good for the liver. Several studies have shown that regular consumptions of foods high in phosphatidylcholine have an effect on the disease activity of many liver disorders. Deficiency in choline results in higher levels of the liver enzyme alanine aminotransferase, which signifies liver damage. This can be easily reversed through major dietary changes. Supplementation has been noted to be very effective in the management of hepatitis infections.

Phosphatidylcholine

You should be taking Phosphatidylcholine Daily to improve Health And Wellness.


What is L-Tryptophan and How Does it Help the Brain, Mood, and Sleep?

L-Tryptophan, Mood, Sleep, and The Brain!

L-tryptophan is an organic compound classified as an essential amino acid. It has a significant presence in the human diet in that it occurs in both animal and plant products. Some of the popular sources are egg, soybean, salmon, chicken, turkey, and pork. Being a biological precursor of the neurotransmitter serotonin, it contributes to the brain processes that create feelings of well-being.

Most of the supplements that contain L-tryptophan are marketed as relaxants. They are even touted to remove sleep disturbances. This amino acid does help the body relax as serotonin plays a pivotal role in maintaining homeostasis. In recent years, L-tryptophan has been associated with the functions of the central nervous system as it appears to be of help to patients afflicted with mental disorders.

L-Tryptophan And The Brain

Affects Brain Chemicals

While tryptophan deficiency is very uncommon in developed countries, and cases in developing countries are also not well understood. Early studies suggest that malnutrition may be the primary reason. That being said, impairment in metabolism such as lactose intolerance and fructose malabsorption has been reported to compromise the absorption of tryptophan in the intestines.

For decades, it has been postulated that a deficiency in tryptophan may result in dementia and dermatitis. Indeed low levels of L-tryptophan in the blood have been linked to attention deficit hyperactivity disorder, bipolar disorder, Alzheimer’s disease, anxiety, and depression. It is one of the amino acids under investigation for its medicinal potential in the treatment of these mental disorders.

Improves Sleep Quality

One of the well established facts about L-tryptophan is its relationship with the neurotransmitter serotonin, which is in fact directly derived from this amino acid. It is also widely accepted that serotonin transmission within the brain is involved in sleep patterns. L-tryptophan raises serotonin levels in the brain and the central nervous system as it is capable of crossing the blood-brain barrier.

More importantly, L-tryptophan is believed to influence physiological responses to outside stimuli as described by the phenomenon called circadian rhythm. It is indispensable in the biosynthesis of melatonin, the hormone that induces feelings of sleepiness and lowers body temperature, effectively regulating the sleep-wake cycle. By influencing releases of melatonin, tryptophan improves sleep.

Counters Stress Factors

Metabolites of L-tryptophan have been extensively utilized by the pharmaceutical industry in the past few years. Supplements that contain serotonin and melatonin a well as tryptophan have become more available today than in previous decades. Supplementation of tryptophan in particular has been observed to help combat stress, suppress appetite, and enhance mood.

L-tryptophan is converted by the human body to 5-hydroxytrytophan, or 5HTP, a metabolic intermediate in the biosynthesis of serotonin and melatonin. It has been well documented that healthy levels of tryptophan and 5HTP benefit people suffering from chronic stress, which lead to physical fatigue characteristic of fibromyalgia. Also, tryptophan has produced positive effects on obesity.

Try L-Tryptophan Today!

If you suffer from lack of sleep give melatonin a try it may help with more then sleep!


How Does the Amino Acid L-Tyrosine Affect Brain Chemistry, Mood, Energy, And More

L-Tyrosine and Mental, Physical Health

L-tyrosine is one of the building blocks of proteins necessary for human life. It is an organic compound quite widespread in nature, for it is abundant in many food products that are readily available such as chicken, fish, milk, cheese, avocados, peanuts, and almonds, among others. In the nervous system, it is central to the production of neurotransmitters. The human body is capable of producing this amino acid, but there are some cases where it fails to metabolize its biological precursor, phenylalanine.

Although not considered an essential amino acid, the biosynthesis of L-tyrosine necessitates the presence of an essential amino acid. People of all ages who suffer from a metabolic disorder that imperils its synthesis are in danger of developing brain damage that leads to seizures, retardation, and cognitive decline. L-tyrosine is indispensable in the manufacture of neurotransmitters and hormones that affects not only brain function but also physical capacity. Here’s why:

L-Tyrosine And Stress

Counteracts Stress Factors

Catecholamines are a group of chemical compounds responsible for physiological responses to stressful conditions, and as such are dubbed “fight or flight” hormones. These hormones produced and released by the adrenal glands enter the circulatory system and act on the nervous system. However, the adrenal glands are not capable of synthesizing catecholamines without L-tyrosine.

First, L-tyrosine is converted into L-DOPA, which crosses the blood-brain barrier and increases the level of catecholamines in the brain and the rest of the central nervous system in response to stress. At the same time, it assists the peripheral nervous system in conditioning the blood vessels and skeletal muscles to respond to stress factors appropriately, allowing us to feel a sudden rush of energy.

L-Tyrosine And Energy

Stimulates the Nervous System

Metabolites of L-tyrosine are often sold as medications with psychoactive properties. In fact, many stimulants and antidepressants are either catecholamine analogues or precursors to catecholamines. Supplementation of L-tyrosine appears to work on the same principle. It influences mood and creates feelings of well-being as it raises the levels of dopamine, norepinephrine, and epinephrine.

In general most of the psychoactive drugs available in the market are considered safe. That being said, many researchers do not discount the fact that they may have adverse effects right after intake or in the long run. One of the most common concerns is their cytotoxic properties, which is tied to the pathogenesis of many diseases. L-tyrosine is believed to be safer in that it provides the biological precursor needed to manufacture brain chemicals in contrast to adding them to the system.

Helps Maintain Concentration

Catecholamines are chemicals that induce neuronal activities. Low levels of catecholamines have been detected in individuals diagnosed with depression whereas the opposite has been observed to have a negative impact on motivation as a behavior. Supplementation of L-tyrosine has been associated with the improvement of cognitive function, such as enhanced mental performance amid repetitive tasks.

If you need a Mood boost, Concentration boost, and energy boost, give L-Tyrosine a try!


How Does Lithium Help the Brain and Mood?

Lithium And Your Mood

Lithium has been used in treatment of bipolar disorder, or BD, far longer than any other mood stabilizer in the market today. In fact, it is the only drug approved for children diagnosed with BD to date. Although it is known to have a quite narrow ratio of being therapeutic to being toxic, most of its side effects are comparable to taking too much table salt. That being said, administrations of lithium often take place in clinics with facilities that are able to monitor lithium levels in the blood.

Physicians in Greek and Roman antiquity prescribed lithium salts to people suffering from bouts of mania and melancholia. At that time there was no distinction made for bipolar disorder as a separate mental illness, but the tranquilizing effects of lithium salts on patients afflicted with depression or mania were well documented. While preparations containing elemental lithium were not yet available in ancient times, physicians instruct patients to drink from alkali springs, which contain high concentrations of lithium salts.

In the first half of the 20th century, the Australian psychiatrist John Cade first noticed that the urate compound in the form of lithium induces tranquility in patients diagnosed with manic tendencies. Soon in 1970 after more thorough studies, the US Food and Drug Administration approved its use for manic illness. Lithium is now the “classic” medication for the present-day classification of bipolar disorder, which refers to the behavioral symptoms of the earlier category of manic depression.

Lithium And Neural Activity

Affects Excitatory Neurotransmitters

The mechanisms of action of lithium as a mood stabilizer is still under scrutiny, but in the past few years a number of theories have gained significant attention. The most prevalent explanation is its effects on the excitatory neurotransmitter glutamate. It is believed that lithium exerts changes in endogenous glutamate by blocking the enzyme responsible for the conversion of gamma-aminobutanoic acid, or GABA, into glutamate. By so doing, lithium raises concentrations of GABA, the chief inhibitory neurotransmitter in the central nervous system.

Lithium and Brain Function

Restores Normal Brain Function

Another conjecture involves GSK-3B enzyme, which influences the circadian rhythm. Lithium ions are believed to produce a regulatory effect on this enzyme, deactivating it when needed. GSK-3B is implicated in a series of chemical reactions implicated in what is called the Wnt signaling pathway, which lithium salts inhibit and consequently create a mood-stabilizing effect. In other words, lithium restores normal processes in the brain that were disrupted by the activation of GSK-3B.

Influences Neural Plasticity

The most recent of these studies postulates that lithium creates a homeostatic effect on nitric oxide and promotes its activities in the nervous system. This is central to the purported role of lithium in neural plasticity, a phenomenon recently observed. These continuing researches as well as anecdotal evidence that are largely positive contribute to the presence of lithium medications in psychiatry. It is a widely accepted fact that lithium is far superior to placebo in reducing mood shifts, the reason why it remains a mainstay of treatment for bipolar disorder.

Lithium is available over the counter in 5mg dosages.  You can find Lithium at your local or internet vitamin store.


Can Phosphatidyl Serine Help with Brain Function and ADHD?

Phosphatidyl Serine Benefits

Phosphatidyl Serine, or PS, has long been touted as one food for the brain, but only recently has it gained a great amount of attention in the scientific community in connection with its potential to alleviate known medical signs afflicting people of all ages. It is widely accepted that PS is a brain chemical, and, when ingested and consequently absorbed, it slows down brain shrinkage tied to cognitive dysfunction in the elderly, as is the case with Alzheimer’s disease. Furthermore, it is considered safe by health organizations from all over the world, and the US FDA has granted it GRAS status, or Generally Recognized As Safe. Following the earlier studies, PS is now in use to treat a neurobehavioral condition known as Attention Deficit Hyperactivity Disorder, or ADHD.

Increases Glucose Metabolism

It is a well established fact that the brain solely relies on glucose for energy while the rest of the body is able to utilize both sugar and fats. It has been postulated that diet plays a role in inducing impulsive and inattentive behavior in kids diagnosed with ADHD in that the absence of nutrients from the foods we eat for prolonged periods of time contribute to how the body processes glucose. With an imbalanced nutrition, the metabolism of glucose tends to cater to those which the body considers at risk of malfunctioning and respond to the needs of other organs to a lesser degree, compromising the glucose needs of the brain. PS is one of those organic compounds that enhances glucose metabolism to meet the brain’s demands, resulting in an uncompromised brain development in children, those children who consume it regularly.

Phosphatidyl Serine – Modulates Neuronal Activities

Metabolites of phosphatidyl serine have been observed to influence the manufacture, release, and activities of neurotransmitters. Clinical trials involving PS began two decades ago, and to date there is considerable data yielded from a number of well designed human studies that unveil the activities of phosphatidyl serine at the cellular level. PS appears to improve the endogenous production of choline, an essential nutrient that has a longstanding association with the ubiquitous neurotransmitter acetylcholine. The availability of these compounds is believed to augment cognitive function in that neuronal activities necessitate their presence. In fact, sustained attention stems from the ability of the body to effectively supply the brain with important chemicals, which includes choline and acetylcholine, and phosphatidyl choline assists the body in this task.

Promotes Cellular Health

Supplementation of phosphatidyl choline encompasses a broad range of benefits to cellular health in addition to its homeostatic effects on the chemicals present in the brain. What remains an undisputed discovery is the role of phosphatidyl choline in the upkeep of every single cell of the human body. Phosphatidyl serine is a major constituent of the endoplasmic leaflet of the lipid bilayer that makes up the cell membranes, and thus interacts with the cytoskeleton in many intracellular processes, even including cell division. Along with other compounds, it maintains a certain level of viscosity needed for cell fluidity, which is of utmost significance for cell signaling.

Phosphatidyl Serine can help the brain function better, are you getting any daily, if not you should be!

 


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